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Steven N. Sireci, M.D. Responds:
Authoritative information on this topic can be obtained in one of two
ways:
- By contacting Bristol-Myers Squibb® the maker of both
of those antidiabetic drugs, and reviewing the package inserts and other
information Bristol-Meyers Squibb may provide about them, and
- By consulting the section entitled "Metformin (Glucophage) Therapy
and the Risk of Lactic Acidosis" found on pages 17-18 in the ACR Manual
on Contrast Media (4th Edition, available from the American College
of Radiology).
The ACR Manual states the following in a summary paragraph on the topic:
"Therefore, metformin should be discontinued before or at the time
of the procedure, withheld for 48 hours after the procedure, and reinstated
only after renal function has been re-evaluated and found to be normal."
Any information supplied by Dr. Sireci through
RadiologyWeb is not to be considered as professional advice being offered
by Dr. Sireci, either on behalf of Bracco Diagnostics or on behalf of
himself individually. The viewer should use any such information and/or
opinions for general reference only. The information is not intended to
provide definitive or complete medical, instructional, or treatment information.
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